A Yale-led study reveals that new medicines and vaccines approved for use in the United States are often unavailable in countries that hosted their clinical trials, suggesting that the benefits of drug research are not being shared equitably among populations that participate in testing.
R21/Matrix-M, a malaria vaccine developed at the Jenner Institute, University of Oxford, showed efficacy of 77% over 12 months in a recently reported phase IIb trial. First vaccinations have now begun in Mali in a larger phase III trial which is hoped to lead to licensure of this malaria vaccine by 2023.
Individuals living with a spouse with heart disease were more than twice as likely to have heart disease themselves, according to a study being presented at the American College of Cardiology's 70th Annual Scientific Session.
Young Black women show a high prevalence of obesity, elevated blood pressure and other lifestyle-related factors that may put them on a trajectory to develop heart disease at a young age, according to a study presented at the American College of Cardiology's 70th Annual Scientific Session.
Breathing in secondhand cigarette smoke may leave you more vulnerable to heart failure, a condition where the heart isn't pumping as well as it should and has a hard time meeting the body's needs, according to a study being presented at the American College of Cardiology's 70th Annual Scientific Session.
People with heart disease are more likely to become seriously ill from the flu and other respiratory illnesses, including the coronavirus. Yet, new research finds that only half of Americans with a history of heart disease or stroke report getting an annual flu shot, despite widespread recommendations to do so. Rates of vaccination were even lower among Blacks and Hispanics, according to data being presented at the American College of Cardiology's 70th Annual Scientific Session.
People with prediabetes were significantly more likely to suffer a heart attack, stroke or other major cardiovascular event when compared with those who had normal blood sugar levels, according to research being presented at the American College of Cardiology's 70th Annual Scientific Session. Researchers said the findings should serve as a wake-up call for clinicians and patients alike to try to prevent prediabetes in the first place.
A large scale trial by Monash University has definitively found a drug commonly used during anaesthesia before surgery to prevent nausea and vomiting does not increase the risk of a surgical wound infection as once feared.
Researchers from the Institute for Bioengineering of Catalonia (IBEC) in collaboration with the INCLIVA Health Research Institute in Valencia, develop the first three-dimensional model for myotonic dystrophy, a rare disease that currently has no cure. The new model combines patient cells and bioengineering techniques and represents a major advance over the use of animals and cell cultures. This new model will help in the design of personalized and more effective treatments, and for drug testing in a much more efficient way.
Researchers are now able to wirelessly record the directly measured brain activity of patients living with Parkinson's disease and to then use that information to adjust the stimulation delivered by an implanted device. Direct recording of deep and surface brain activity offers a unique look into the underlying causes of many brain disorders; however, technological challenges up to this point have limited direct human brain recordings to relatively short periods of time in controlled clinical settings.