Children who consume too much sugar could be at greater risk of becoming obese, hyperactive, and cognitively impaired, as adults, according to the results of a new Australian study of mice led by QUT.
The experimental, lab-made antibody leronlimab can completely prevent nonhuman primates from being infected with the monkey form of HIV, new research published in Nature Communications shows. The results will inform a future human clinical trial evaluating leronlimab as a potential pre-exposure prophylaxis, or PrEP, therapy to prevent human infection from the virus that causes AIDS.
In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.
Vaccines are critical tools for fighting COVID-19, and new vaccines will expand overall vaccine availability. In an article recently published in Chinese Medical Journal, a research team use phase 1 and 2 clinical trial data to show that a vaccine called KCONVAC, which contains an inactivated virus, is safe and can stimulate antibody production. These findings support the initiation of a phase 3 trial to confirm that the vaccine is safe and effective.
In a current study published in Scientific Reports, researchers from University of Southern Denmark and Karolinska Institutet in Sweden investigated the effects of lifelong regular exercise on two of the central hallmarks of aging combined and showed that football and team handball have a positive effect on telomere length and mitochondrial function in women.
Researchers at the Finnish Center for Artificial Intelligence have developed a machine learning-based method that produces synthetic data on the basis of original data sets, making it possible for researchers to share their data with one other. This could solve the ongoing problem of data scarcity in medical research and other fields where information is sensitive.
A world-first international study led by the University of South Australia has identified a new drug to stop athletes developing dementia after sustaining repeated head injuries in their career.
New research suggests that measuring how patterns of gene expression in white blood cells change in children starting in infancy - before autoantibodies appear indicating an autoimmune reaction against pancreatic β cells - can predict earlier and more robustly which genetically-susceptible individuals will progress to T1D. The international study, based on blood samples longitudinally collected from 400 children in The Environmental Determinants of Diabetes in the Young (TEDDY) consortium, included co-investigators from the University of South Florida Health Informatics Institute.
The June edition of SLAS Technology is a Special Issue entitled, 'Emerging Trends in 3D Cell Culture: High-Throughput Screening, Disease Modeling and Translational Medicine.' Free online access to the articles in this collection is courtesy of Corning Life Sciences, the issue's sponsor.
A phase III clinical trial led by an investigator at the Medical University of South Carolina found that a novel four-month regimen was just as effective at treating tuberculosis as the standard six-month regimen. The findings are reported in the May 6, 2021 New England Journal of Medicine.