A team of neuroscientists are calling for greater support of neuroscience research in Africa to combat 'brain drain' following a long-term analysis of research outputs in the continent.
In a Journal of Neuroimaging analysis of data obtained from 193 patients with COVID-19 who had brain and/or spine imaging and a lumbar puncture because of neurologic symptoms, investigators found that imaging results were related to the presence of SARS-CoV-2 in the cerebrospinal fluid.
Therapy based on the Nintendo® Wii Balance Board can help improve balance in children with cerebral palsy, according to an analysis published in Developmental Medicine & Child Neurology.
A new study at the University of Chicago Medicine and Washington University found that a single inhalation session with 25% nitrous oxide gas was nearly as effective as 50% nitrous oxide at rapidly relieving symptoms of treatment-resistant depression, with fewer adverse side effects.
QurAlis Corporation today announced the publication of an article in Cell Reports titled Human Amyotrophic Lateral Sclerosis Excitability Phenotype Screen: Target Discovery and Validation by QurAlis founders Kasper Roet, Ph.D., Clifford Woolf, M.D., Ph.D., and Kevin Eggan, Ph.D., who pioneered a high-content, live-cell imaging screen using ALS patient-derived motor neurons in combination with a compound library generated by Pfizer to identify drug targets to treat hyperexcitability induced neurodegeneration in ALS patients.
New molecules, developed by researchers at Linköping University, Sweden, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects.
A new study from a CUNY ASRC Neuroscience Initiative team has identified a molecule called ten-eleven-translocation 1 (TET1) as a necessary component in the repair of myelin, which protects nerves and facilitates accurate transmission of electrical signals. The discovery could have important implications in treating neurodegenerative diseases and for molecular rejuvenation of aging brains in healthy individuals.
Scientists from the Immuno-Pharmacology and Interactomics group at the Luxembourg Institute of Health (LIH), in collaboration with the Center for Drug Discovery at RTI International (RTI), have demonstrated that conolidine, a natural painkiller derived from the pinwheel flower and traditionally used in Chinese medicine, interacts with the newly identified opioid receptor ACKR3/CXCR7 that regulates opioid peptides naturally produced in the brain. The researchers also developed a synthetic analogue of conolidine, RTI-5152-12, which displays an even greater activity on the receptor.
For decades, researchers have debated whether the buildup of certain electrical activities in the brain indicates that human beings are unable to act out of free will. A new article argues that recent research undermines this case against free will.
Psychotic disorders comes with a progressive decline in IQ. If current drug treatments are successful in containing psychotic symptoms, nothing can be done to prevent the deterioration of intellectual skills that leads to loss of autonomy. Researchers (UNIGE) have discovered that prescription of selective serotonin reuptake inhibitors (SSRIs) in late childhood can reduce the deterioration of intellectual abilities and have a neuroprotective effect on some of the brain regions affected by the psychotic illness.