The dynamics of the neural activity of a mouse brain behave in a peculiar, unexpected way that can be theoretically modeled without any fine tuning, suggests a new paper by physicists at Emory University. Physical Review Letters published the research, which adds to the evidence that theoretical physics frameworks may aid in the understanding of large-scale brain activity.
Triple-negative breast cancer is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory. A research team led by biologists at City University of Hong Kong (CityU) has identified and characterised a set of specific super-enhancers that stimulate the activity of the related critical cancer genes. The latest findings may help discover new effective drug targets for TNBC patients to improve their survival chance.
An article published in the journal EBiomedicine by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, shows that the epigenetic endowment of each person influences the severity of the COVID-19 disease.
Bird genomes contain surprisingly few tRNA genes, suggesting that they have evolved to use their limited tRNA repertoire more efficiently.
Researchers have identified molecular signatures of the aging process in mice.
Selecting the right deconvolution method to analyze the composition of complex mixtures of cells just got easier. Researchers at Baylor College of Medicine derived clear guidelines scientists can use to determine the deconvolution method that optimally fits their needs.
MDC researchers can now induce diverse genetic mutations and track their effects on a large scale in microscopic worms. The team describe their in vivo parallel genetics approach and new analysis software called crispr-DART in the journal Cell Reports.
What exactly happens when the corona virus SARS-CoV-2 infects a cell? In Nature, a team from the Technical University of Munich (TUM) and the Max Planck Institute of Biochemistry paints a comprehensive picture of the viral infection process. For the first time, the interaction between the coronavirus and a cell is documented at five distinct proteomics levels. This knowledge will help to gain a better understanding of the virus and find starting points for therapies.
Researchers have independently validated industry-leading blood tests that can detect the DNA released by tumours.
The network of nerves connecting our eyes to our brains is sophisticated and researchers have now shown that it evolved much earlier than previously thought, thanks to an unexpected source: the gar fish.