Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.
Surgical smoke poses a health risk to everyone in the operating room. Perioperative teams exposed to surgical smoke report twice as many respiratory health issues as the general public. The smoke can even contain viruses. Researchers suggest that policies and laws mandating the evacuation of surgical smoke from operating rooms are the best way to reduce the negative health impacts on perioperative staff as well as surgical patients.
New toxin-antidote pairs discovered in nematode species - researchers from the Burga lab at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences discover selfish elements that could facilitate populations becoming distinct species. The results are published in the journal Current Biology.
Published research shows a new "Trojan horse" approach that produces strong antidotal efficacy in treating lethal botulism.
Preclinical data published in Science Translational Medicine showed that post-symptomatic administration of Cyto-111 produced antidotal rescue in three animal species following a lethal botulism challenge. Study authors concluded, " atoxic BoNT derivatives can be harnessed to deliver therapeutic protein moieties to the neuronal cytoplasm where they bind and neutralize intracellular targets in experimental models. The generalizability of this platform might enable delivery of antibodies and other protein-based therapeutics to previously inaccessible intraneuronal targets."
Research at the University of Cincinnati, however, contends that this antiviral drug is being used too indiscriminately when treating patients hospitalized with the virus. The study is published in the journal Fundamental & Clinical Pharmacology.
When agrochemical and pharmaceutical companies develop new products, they must test extensively for potential toxicity before obtaining regulatory approval. This testing usually involves lengthy and expensive animal studies. A research team at University of Illinois has developed a gene biomarker identification technique that cuts the testing process down to a few days while maintaining a high level of accuracy.
Scientists have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure. 'We expect that the genetically encoded photosensitizer SuperNova2 will find use in a wide range of experimental models,' Konstantin Lukyanov, a professor at the Skoltech Center of Life Sciences (CLS), comments.
A protein responsible for orchestrating DNA key signaling and repair pathways could play a role in future chemotherapy treatment for cancer patients. The protein's function has been described by researchers at University of Copenhagen.
In an effort to understand the potential risks associated with exposure to micro/nanoplastics, the?Emerging Risks of Micro/nanoplastics: Perspectives From Diverse Sectors symposia at the 2020 Society for Risk Analysis virtual Annual Meeting, December 13-17, 2020,?aims to highlight the current state of knowledge associated with physical and chemical transformation, hazard characterization, environmental effects, social implications and policy limitations.?