The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow its growth.
The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'. The study has been published in Science Advances.
The lab of Srikanth Singamaneni at the McKelvey School of Engineering at Washington University in St. Louis developed a biosensing microneedle patch that can be applied to the skin, capture a biomarker of interest and, thanks to its unprecedented sensitivity, allow clinicians to detect its presence.
New research shows that non-steroidal anti-inflammatory drugs (NSAIDs) reduced both antibody and inflammatory responses to SARS-CoV-2 infection in mice. The study appears this week in the Journal of Virology, a publication of the American Society for Microbiology.
Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later.
Laser beams are used to change the properties of materials in an extremely precise way. However, the underlying processes generally take place at such unimaginably fast speeds and at such a small scale that they have so far eluded direct observation. Göttingen researchers have now managed to film, for the first time, the laser transformation of a crystal structure with nanometre resolution and in slow motion in an electron microscope. The results were published in Science.
When Mount Pinatubo exploded in 1990, the surrounding Philippine ecosystem was devastated. Scientists thought that the Pinatubo volcano mouse that lived there went extinct. But researchers just discovered the volcano mouse alive and well.
Human activities might have shifted the movement of caribou in and near the Arctic National Wildlife Refuge, according to scientists who tracked them using isotopic analysis from shed antlers. The study is timely given the auction this year of oil and gas leases in the Arctic National Wildlife Refuge. Indigenous Alaskans opposed the leases, arguing development could disrupt the migration of caribou they depend on for sustenance.
Recently named a Web of Science 2020 Highly Cited Researcher, Yiping Qi of the University of Maryland already has a new high-profile publication in 2021 introducing SpRY, a newly engineered variant of the famed gene editing tool CRISPR-Cas9. SpRY removes the barriers of what can and can't be targeted for gene editing, making it possible for the first time to target nearly any genomic sequence in plants for potential mutation.
New research reveals how proteins, called 'pioneer transcription factors,' help turn on key genes that give cell types their unique properties and functions.