For the first time, researchers at Penn Medicine created organoids of the arcuate nucleus (ARC),providing an atlas of cell types in the human hypothalamus, which will be a blueprint to further understanding the development of brain disorders, such as certain causes of obesity and autism.
Endometriosis, a disease found in up to 10 per cent of women, has been enigmatic since it was first described. A new theory developed by researchers at Simon Fraser University suggests a previously overlooked hormone -- testosterone -- has a critical role in its development. The research could have direct impacts on diagnosis and treatment of the disease, signaling hope for women with endometriosis worldwide.
How does whale watching affect whale behavior? Who watches whales in Panama's Las Perlas Archipelago? Researchers from STRI and ASU hope to recommend innovative data-based conservation strategies.
New data on the growth rates of coral reefs shows there is still a window of opportunity to save them from eroding by mid-century--but time is running out.
Captive pelicans that are free to choose their own friendships are more likely to breed successfully on repeated occasions, new research suggests.
The process of combining maternal and paternal genetic information is surprisingly error-prone
A research group led by Dr. Hideyuki Kobayashi at Toho University Omori Medical Center in Tokyo developed an AI-assisted image classifier that provides scores for histological testis images of patients with azoospermia. The objective of Dr. Kobayashi, a urologist, was to create an easy-to-use method of pathological examination for the daily clinical practice setting. With it, testis images could be classified at 82.6% accuracy.
The world's largest terrestrial conservation area is located in southern Africa and covers 520,000 square kilometers spanning five countries. A study from the University of Zurich now shows that the endangered African wild dog mostly remains within the boundaries of the Kavango-Zambezi Transfrontier Conservation Area (KAZA) when dispersing, thus highlighting the relevance of such a large-scale conservation initiative for maintaining key wildlife corridors of threatened species.
Mutations in a protein called GEMIN5 cause developmental delay and loss of coordination in young children.
Early in fetal development, a mass of cells known as the bipotential gonad has the possibility of giving rise either to ovaries or testes, reproductive organs that contribute to many of the characteristics that define a person's sex. In a new study, the University of Pennsylvania's Kotaro Sasaki and colleagues pinpoint the origins of that precursor gland.