A new gene therapy for one of the most common forms of congenital blindness was safe and improved patients' vision, according to initial data from a clinical trial
A joint research carried out by MIPT scientists and Harvard researchers have presented retinal cells that can integrate into the retina. This is the first successful attempt to transplant ganglion cells (retinal neurons that are destroyed by glaucoma) derived from stem cells in a lab setting. Scientists tested the technology in mice and established that the cells successfully integrated and survived for a year. In the future, the researchers plan to create specialized cell banks, which will permit individual, tailored therapy for each patient.
The national Ocular Hypertension Treatment Study was designed to determine whether lowering elevated eye pressure in patients might prevent vision loss from glaucoma. Researchers recently completed follow-up studies on patients 20 years after the start of the original study and found that not all patients with elevated eye pressure need pressure-lowering treatment to prevent vision loss from glaucoma.
A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.
A chemical known to protect nerve cells also slows glaucoma, the leading cause of irreversible blindness, results of a new study in rats show.
Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration--the leading cause of blindness among older adults. The UMSOM researchers say that the findings suggest a new and distinct cause that is different from the previous model of a problematic immune system, showing that the structural organization of the eye's light-detecting cells may be affected by the disease.
Researchers developed an experimentally validated advanced computer model that reproduces the shapes and positions of millions of nerve cells in the eye, as well as the physical and networking properties associated with them. Focusing on models of nerve cells that transmit visual information from the eye to the brain, the researchers identified ways to potentially increase clarity and grant color vision to future retinal prosthetic devices.
This case series examines whether maternal SARS-CoV-2 is associated with outcomes in the eyes of their newborns.
A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.
A Scientific E-Poster to be presented at the 2021 ARRS Virtual Annual Meeting found the COVID-19 'Safer at Home' order resulted in a significant decline in radiology ordering utilization, outpatient consultations, and emergency department (ED) visits.