A survey of U.S. multiple sclerosis, or MS, specialist clinicians reveals the COVID-19 pandemic has created major changes in how they deliver care. More than 95% of survey respondents reported using telehealth platforms to provide care for their patients. Approximately one half of the respondents were MS specialist neurologists, four out of five of whom indicated that COVID-19 had changed how they were recommending and prescribing MS disease-modifying therapies.
Researchers at Kanazawa University report in the Japan Journal of Nursing Science a study of muscle pump action in the context of chronic lower-limb edema. They found that body posture and exercise habits affect the blood pumping action of muscles in the leg, whereas age generally does not.
The new cutoff values for a metric widely used by geriatricians, physical therapists and nutritionists are more accurate, facilitate early diagnosis and contribute to preventive treatment.
New research shows that a novel positron emission tomography (PET) tracer that targets inflammation is safe and can clearly identify early stages of rheumatoid arthritis. The promising PET tracer, 68Ga-DOTA-Siglec-9, rapidly clears from blood circulation, has a low radiation dose, and can be easily produced. This first-in-human study was published in the April issue of The Journal of Nuclear Medicine.
Researchers at the University of Tsukuba have shown that an exercise regimen reduces liver steatosis and stiffness in patients with non-alcoholic fatty liver disease. These gains in hepatic health are mediated through modification of inter-organ cross-talk, circulatory organokine alterations and reductions in inflammation and oxidative stress. Because these benefits are unrelated to weight loss, all therapeutic regimens should integrate regular exercise and patients should remain diligent and compliant regardless of bodyweight changes.
The scientists detected incapacities related to gait timing and foot placement. Their discoveries serve as a basis for the development of an exercise protocol that mitigates the difficulty.
A new study published in the Journal of Bone and Mineral Research has examined the effects of type 1 diabetes and diabetic neuropathy on the skeleton.
The rarity of spinal muscular atrophy (SMA) means that promising new treatments may be tested in only a limited spectrum of patients before approval. Investigators evaluated a newly approved drug, onasemnogene abeparvovec, in a broader spectrum of patients in order to obtain expanded data on its side effects profile.
A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training. The intervention involved a standard strength-training protocol with sessions three times per week. None of the participants had previous weightlifting experience.
A UCLA-led research team has identified a chemical cocktail that enables the production of large numbers of muscle stem cells, which can self-renew and give rise to all types of skeletal muscle cells.