A new publication offers a comprehensive guide to help plant scientists communicate their work to the world. An Iowa State University scientist who contributed to the multi-institutional effort says it's critical that plant scientists emphasize outreach to make sure plant science is able to meet the demands of climate change and population growth.
Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.
The researchers have discovered that USP7 inhibitors -under development by several pharmaceutical companies for the treatment of cancer- trigger a premature activation of cell cycle proteins, leading to uncontrolled cancer cell division and death. * The paper rejects the premise that the therapeutic efficacy of these inhibitors is due to their effects on activating the tumor suppressor protein P53, as currently accepted by the international scientific community. These results extend the potential use of USP7 inhibitors to a wider range of patients.
Oblique Therapeutics AB, a Sweden-based biotech company, in collaboration with Karolinska Institutet (Stockholm, Sweden), Gothenburg University (Sweden) and several local biotechs published promising research results in the highly-acclaimed scientific journal Science Advances (AAAS) entitled: Rational Antibody design for Undruggable Targets using Kinetically Controlled Biomolecular probes.
Early in the COVID-19 pandemic, doctors recognized that patients who developed a "cytokine storm" -- a surge of pro-inflammatory immune proteins -- were often the sickest. But a cytokine storm can also occur in other illnesses, such as influenza. Now, scientists report a sweat sensor that acts as an early warning system for an impending cytokine storm, which could help doctors more effectively treat patients. The researchers will present their results today at ACS Spring 2021.
Researchers at The University of South Australia's Future Industries Institute have developed technology that could eliminate water stress for millions of people, including those living in many of the planet's most vulnerable and disadvantaged communities.
What are the most effective ways to leverage and augment smartphone capabilities? Helpful guidelines are provided in a critical review of emerging smartphone-based imaging systems recently published in the Journal of Biomedical Optics (JBO).
Reliance on petroleum fuels and raging wildfires: Two separate, large-scale challenges that could be addressed by one scientific breakthrough. Researchers from two national laboratories have collaborated to develop a streamlined and efficient process for converting woody plant matter like forest overgrowth and agricultural waste - material that is currently burned either intentionally or unintentionally - into liquid biofuel.
Scientists have been exploring the cellular mechanisms underlying cancers for centuries in an attempt to successfully treat them. Collating recent research on one avenue of this exploration, the role of cell membrane receptor neuropilin-1, a review article published in Chinese Medical Journal gives a glimpse of how much we know of the disease, how much we still need to find out, and new promising treatments that we've begun to apply.
Drones could soon be adopted as essential tools for various agricultural tasks; however, with respect to their use in farm management, research is still lacking. To address this issue, researchers in Japan compared drones to well-established technologies for spraying pesticide over rice paddy fields. Using statistical data, the researchers explore both advantages and limitations of drones and whether they currently offer an edge regarding costs, capacity, and management efficiency.